Dr. Giles is an Associate Professor of Medicine and Director of the Inflammatory Arthritis Center at Cedars-Sinai Medical Center in Los Angeles, California. He is also Co-Director of the Rheumatoid Arthritis Translational Research Program in the Kao Autoimmunity Institute at Cedars-Sinai. He obtained his BA in biochemistry from the University of Virginia, Charlottesville, VA, his MD from Vanderbilt University, Nashville, TN and his MPH from Johns Hopkins University, Baltimore, MD. Dr Giles went on to complete his residency in internal medicine at the University of California San Diego, San Diego, CA and his fellowship in rheumatology at Johns Hopkins University.

Dr Giles’s research interests are centered primarily within the inflammatory arthritides. Recent projects center around understanding how inflammation affects adipose tissue and muscle in people with rheumatoid arthritis (RA) and psoriatic arthritis, and their subsequent effects on health outcomes. Other current and past research interests involve the investigation of accelerated atherosclerosis and myocardial dysfunction in patients with RA, understanding the determinants of RA-associated interstitial lung disease, and exploring the musculoskeletal side-effects of a class of medications used to suppress estrogen in women with certain forms of breast cancer. Dr Giles is currently initiating studies exploring the effect of neuroactivation of brain areas associated with stress and anxiety on how people with RA respond to treatment. Additional current research projects involve deriving a prediction model for deciding which RA patients will benefit from statin therapy to reduce cardiovascular events.

Dr Giles is the recipient of grant support from the National Institutes of Health, the Arthritis Foundation, the Rheumatology Research Foundation, the Maryann Legato Foundation for Gender-Specific Medicine and the Arthritis National Research Foundation.